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Loann Goujon comes into the French starting XV in place of Damien Chouly at flanker in the sole change to a team that were brilliant at Twickenham last weekend despite falling to a 19-16 defeat against England.
Scotland's only change also comes at blindside flanker, with John Barclay replacing the injured Ryan Wilson and Edinburgh flanker John Hardie taking up the 56-cap flanker's spot on the bench.
Fraser Brown and Finn Russell have both shrugged off knocks to start for Vern Cotter's side, Brown pulling on the No.2 shirt despite Ross Ford's showing from the bench against Ireland.
Guy Noves has resisted the temptation to heavily tinker with Les Bleus, as 22-year-old Bordeaux-Begles scrum-half Baptiste Serin retains his place alongside Camille Lopez in the half-backs.
Guy Noves (France): "This change strengthens the pack, even if the profiles of Chouly and de Goujon are essentially identical.
"We will mainly adapt to the Scottish rugby that you have seen evolve for four years. A game based on commitment, speed, aggression, with players who have gained confidence in a highly organised collective."
Vern Cotter (Scotland): "France in Paris is a monumental challenge.
"We'll have to match their ferocity while ensuring we take that - and all the other battles we can expect in this game - on our terms, whether that's in collisions, in set-piece, at the breakdown or in the air.
"We will need to be at our relentless best once again."
Louis Picamoles v John Barclay:
Though John Barclay's inclusion was forced by Ryan Wilson's absence, the Scarlet has - along with Hamish Watson - the unenviable task of trying to tie up France's marauding No.8 Louis Picamoles.
The Northampton Saints back row ran for more metres than the entire England pack, lead the round for offloads and was named man of the match in defeat.
Barclay showed in the autumn how effective he can be against high-class opposition, tying up Lopeti Timani, Michael Hooper and David Pocock admirably well in a 23-22 defeat.
Picamoles provides France with so much go-forward ball and seemingly never fails to make the advantage line.
If Scotland are to sustain their challenge over 80 minutes, they must subdue Picamoles and in Barclay they could have a potent antidote.
Stat Watch: Scotland's starting back five of Jonny Gray, Richie Gray, Ryan Wilson, Hamish Watson and Josh Strauss made 102 tackles against Ireland.
Their opposite numbers for France were forced into making just 47 against England. Defending for long periods is notoriously draining, meaning Les Bleus' comparative freshness could be influential in the latter stages in Paris.
Fantasy Watch:
Click here to play the 2017 RBS 6 Nations Fantasy Game
Though Wales' Leigh Halfpenny was top of the fantasy pile in terms of points scored last weekend, Stuart Hogg's two-try heroics meant he finished up just half a point behind the Welsh full-back.
As second overall, he is an obvious pick, while at just 11 stars, Alex Dunbar represents excellent value in the centres.
Jonny and Richie Gray finished 17th and 22nd respectively in the fantasy charts, bettered only by Cory Hill and Alun Wyn Jones in the second-row stakes.
For France, Louis Picamoles finished up 13th overall - the highest of any Frenchman - while Scott Spedding is another potential option at full-back.
France v Scotland
12 February
Stade de France
Kick-off:16:00 (local)
TV: FR2, BBC, RTE, DMAX, ITV (H)
Click here for the complete 2017 RBS 6 Nations fixture list with TV schedule
