| Date |
| Time (Local) | (GMT) |
| Home | Home | Score | Away | Away |
| Venue |
| TV |
|
|---|
| Round 1 |
| 04/02/2018 | 04/02 | 16:00 | 15:00 |  | Italy | Ita | 15 - 46 | England | Eng |  | Stadio Olimpico |
|
| Report | Stats |
| Round 2 |
| 10/02/2018 | 10/02 | 14:15 | 14:15 |  | Ireland | Ire | 56 - 19 | Italy | Ita | | Aviva Stadium |
|
| Report | Stats |
| Round 3 |
| 23/02/2018 | 23/02 | 21:00 | 20:00 |  | France | Fra | 34 - 17 | Italy | Ita | | Orange Vélodrome |
|
| Report | Stats |
| Round 4 |
| 11/03/2018 | 11/03 | 15:00 | 15:00 |  | Wales | Wal | 38 - 14 | Italy | Ita | | Principality Stadium |
|
| Report | Stats |
| Round 5 |
| 17/03/2018 | 17/03 | 13:30 | 12:30 | | Italy | Ita | 27 - 29 | Scotland | Sco |  | Stadio Olimpico |
|
| Report | Stats |
|
